The notorious serial killer, Howard Epps, sets his prison cell on fire as part of a daring prison escape. Brennan is his target and her entire team is placed in danger.
Sookie acts strangely. Luke attends his court case hearing. Lorelai is confronted about the character reference letter she wrote for Luke.
While House is forced to work full-time in the clinic and deal with a rape victim who insists on confiding with him, Cameron deals with a terminal cancer patient trying to take advantage of her state of mind.
Mike joins the Bowie BaySox team at Prince Georges Stadium in Maryland acting as a groundskeeper. Next he fixes boat moorings with a former Navy SEAL. He then joins Watson Water company dig deep through mud, rock, gravel, sand and water as they drill for heating and water in Tennessee. Also, Mike takes a dive into the mail bag.
This episode demonstrates the production processes for horseshoes, dishwashers, graphite fly rods and pizza, and shows how each is made.
Veronica is hired to track down a one-night-stand, but the situation becomes more complicated when she turns out to be a hooker. Meanwhile, Keith continues his investigation in Dean O'Dell's death, and a visit by Madison Sinclair causes trouble for Veronica and Logan.
Ian gets more than he bargained for when a new person enters his life. Another death in the Maguire household causes Mimi to think the family may be cursed.
To catch a predator shows us the investigations carried out using the hidden camera from Dateline NBC.
Lucy publishes photos of action-movie star Jack Dawson in the arms of her brother Leo; menacing visitors threaten Brent Barrow to reveal Lucy's source about the murder of Aundre G; Julia interrupts a photo shoot for Holt.
The Most Haunted team investigate ghostly activity at one of the UKs most popular theme parks.
Denny goes ape when Bella is the target of animal-rights activists, who are being represented by her daughter--and his diminutive ex-girlfriend--Bethany. Meanwhile, Brad has doubts about his secret trysts with Denise; Claire is surprised by a new suitor; and Paul believes a costume party will raise everyone's spirits.
While Eddie and Lund investigate a murder outside of a Chinese restaurant, Jenn's sister is targeted by a stalker who doesn't take no for an answer. With an obsession and desperation greater than anyone expected, a few lives could be at risk. Eddie and Jenn are forced to intervene.
Maya fears Jabari is growing up too fast. Joan is uncomfortable about using the bathroom at Aaron's house. Monica and William ask Lynn for sex advice.
Jack finds himself confronting his father while the lead terrorist needs help if he's to explode the remaining bombs.
In Mexico, Sucre gets a car but gets in trouble by the police. Bellick has more trouble as the new inmate as prisoners who suffered with him want revenge.
Hiro continues to search for a sword while being chased by mysterious figures. An invisible man named Claude has something to teach one of the heroes. D.L. takes on new family responsibilities, and Matt opens up to his wife. H.R.G. continues to focus on the captive Sylar. Claire seeks out the Haitian and then her birth parents. Mohinder looks for those on the list, and receives a surprise visitor. A psychiatrist offers to help Niki.
Chris gets no respect when he has hall monitor duty. Greg tells him to "step up his game" but the power goes to Chris' head and he could lose Greg as his friend. Tonya finds out her popularity is because the girls want to get close to Drew.
Hopper unexpectedly meets again with Jared - the guy who bit him in the fifth episode - and finds out that he is not the only one reliving the day over and over again. He also finds out that there was an eye-witness and that he was identified as Garza's murderer, while realizing that he has to deal with very powerful people. He also learns that people that are close to him might know more than they say they do.
Heidi throws a party for her birthday where Audrina shows up to try and make amends. However, Heidi refuses to listen.
Little Sean, at just four years old, is the dictator of the Haines household, and every family member bows to his whims. He has more power than he knows what do with, and crying, whining, hitting, spitting, punching, kicking and biting seem to be his preferred methods of communication. Dad Shane is a tough police officer on the job, but he has no authority at home, and Mom Suzanne, an ER nurse, claims that giving in is easier than fighting. Big brother Seth (10) has grown resentful because Sean gets the majority of his parents' attention, so Seth antagonizes Sean to get some attention of his own. Mom and Dad's passivity when it comes to discipline has enabled the boys to spiral out of control, often out of sheer boredom and restlessness.