Trip boards an alien cargo vessel to help repair a stasis pod, which holds a beautiful woman in suspended animation. When the woman accidentally wakes up, she reveals she's not a passenger, but a prisoner.
Grissom, Warrick, and Nick investigate the case of man who apparently was murdered and pushed off a six story building. Grissom's involvement is cut short by renewed hearing problems. Catherine looks into the murder of man outside of his regular bar.
In an effort to redeem himself days before Christmas, Cartman decides to bring Christmas to the Iraqis. So, along with Stan, Kyle, and Kenny they catch a ride with Mr. Hankey to the North Pole to bring Christmas to Iraq.
Lloyd returns to Stuckeyville, and his new scheme is selling makeup for men. When he's prosecuted for being part of a pyramid scheme, Ed doubts Lloyd's claims that he knew nothing about it, creating friction between the brothers. After Mark's father has a heart attack and Mark gets bad news about his own health at his annual checkup, Mike and Warren convince him to have gastric bypass surgery. Ed and Carol smooth over the rough patch in their relationship and become friendly again.
Don Rickles plays a neighbor who dispenses some unorthodox advice when Bernie is told he has high cholesterol. Though it's a sore shoulder and badgering from Wanda that sends Bernie to the doctor, he comes away sore at the physician for weighing him down with bad news. The problem can be controlled through diet and exercise, but that would mean avoiding the finer things to which Mac is accustomed... like fries from Royal Burger. But neighborly Don Rickles suggests that stress is the real problem, and what causes stress? Why, dieting, of course! And that's the case Bernie presents to an incredulous Wanda.
The smoldering corpse of an Asian girl found outside the Chinese consul general's apartment leads the detectives to believe she had made a political statement. When forensics shows that she had been murdered beforehand, they find themselves in the middle of a religious conflict with the consul general their prime suspect and his attorney an old friend of District Attorney Branch.
It's December 23, and the holiday brings several visitors to the White House: Zoey comes home with her new French boyfriend in tow; aided by Josh, Toby's father seeks a reconciliation; and Danny arrives bearing gifts of gold and a heads-up for C.J. about Shareef's death. Will moves into Sam's office at Toby's insistence, and is treated to some good-natured ribbing by the rest of the staff. Bartlet and Leo try to exorcise their guilt about Shareef by adding eleventh hour funding to combat infant mortality in the federal budget, and promoting peace in the Mideast, respectively.
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
Frasier and Niles bicker over who gets to host the family Christmas celebration. When it seems that Martin will have to work, they decide to bring Christmas to him, with disastrous results. Meanwhile, Roz finds herself attracted to a hunky shopping mall Santa.
Andy and Theo move out. Tony thinks about calling it a day with his ex-wife. Sipowicz and Clark Jr look into the threats made to Clark Sr. A distressed, schizophrenic young man keeps saying "she can't breathe".
While Kelly heads to Europe for press and Jack films a guest spot on Dawson’s Creek in North Carolina, Ozzy tries to lift Sharon’s spirits by building a beachside fire so she can enjoy the outdoors.
Charlie and Lisa learn about their daughter Allie's amazing powers while trapped in a perilous situation. Mary Crawford lays the groundwork to snatch the child for government research.
Nick takes the case of a 16 year old mom who wants to put her baby up for adoption, after her father ends up being arrested for the murder of the 16 year old's very ill mom. Brian Olsen (LuLu's Husband) ends up being accused of negligence.
Jack forces Nina to help with a sting operation against her contact in the hopes that he can lead them to the bomb. Palmer and Mike try to gage Stanton's loyalty when they investigate the chopper crash. George has a final conversation with his son.
Paul tries to find perfect gifts for the family to make up for last year's Christmas fiasco. Kerry finds a stray dog during the holidays. Cate is overjoyed when she is asked to sing a solo at the church's midnight service, but fears that seeing her family there will make her nervous.
Misty has returned to Cerulean City to step in as the Cerulean Gym Leader. But as soon as she arrives, she hears a news report about the Pokémon Investigation Agency closing Gyms that fail to meet proper standards—and rumor says Cerulean City is their next stop! Unaware that three of her enemies are in town, Misty rushes to the Gym and finds an out-of-control Gyarados in the pool. Neither Nurse Joy nor her sister's fan club can control it, and she can't just stick it in its Poké Ball while it's still upset. It's Misty's duty as Gym Leader to solve the problem, except she's also had a Gyarados phobia ever since she was a baby! Misty puts on a water show costume and swims in the pool, hoping to stir Gyarados's memories of performing together back when it was a Magikarp. Instead, Gyarados turns the pool into a raging whirlpool, and Misty blacks out. As her Horsea rescues her, she dreams of Ash and Brock telling her she can do this on her own.
Cheryl and the kids are invited to a neighbor's annual Christmas party, but Jim, who is feuding with the neighbor, isn't invited.
A business trip to France is at stake as Andy and Byron jockey for Jessica's favor, with Andy promising to care for her cat, which he loses.